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Article

Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension.

Pharmacogenomics - 1 Nov 2009

Wilke Russell A, Simpson Robert U, Mukesh Bickol N, Bhupathi Satya V, Dart Richard A, Ghebranious Nader R, McCarty Catherine A

Abstract excerpt

AIMS: We tested the hypothesis that genetic variation in vitamin D-dependent signaling is associated with congestive heart failure in human subjects with hypertension. MATERIALS & METHODS: Functional polymorphisms were selected from five candidate genes: CYP27B1, CYP24A1, VDR, REN and ACE. Using the Marshfield Clinic Personalized Medicine Research Project, we genotyped 205 subjects with hypertension and...

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 19891555
DOI: 10.2217/pgs.09.101
PMCID: PMC2974901

Genes

ACE
REN
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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