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Fok I and Bsm I gene polymorphism of vitamin D receptor and essential hypertension: a mechanistic link

1 Jan 2023

Abstract excerpt

The vitamin D receptor (VDR) gene serves as a good candidate gene for susceptibility to essential hypertension. The gene regulates the renin angiotensin system by influencing blood pressure regulation. Around 3% of the human genome is regulated by the vitamin D endocrine system. Several studies have reported mixed results with respect to relationship of VDR gene and hypertension. Observational evidence supports...

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PMID: 36788562
DOI: 10.1186/s40885-022-00229-y

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