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Article

Rapid and specific detection of amantadine-resistant influenza A viruses with a Ser31Asn mutation by the cycling probe method.

Journal of clinical microbiology - 1 Jan 2010

Suzuki Yasushi, Saito Reiko, Zaraket Hassan, Dapat Clyde, Caperig-Dapat Isolde, Suzuki Hiroshi

Abstract excerpt

Amantadine is one of the antiviral agents used to treat influenza A virus infections, but resistant strains have widely emerged worldwide. In the present study, we developed a novel method to detect amantadine-resistant strains harboring the Ser31Asn mutation in the M2 gene based on the cycling probe method and real-time PCR. We also studied the rate of amantadine resistance in the 2007-2008 influenza season in...

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Source

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Identifiers

PMID: 19889895
DOI: 10.1128/JCM.00698-09
PMCID: PMC2812285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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