Article
[Resistance to amantadine of epidemic strain of H3 subtype influenza virus: a primary study].
Zhonghua yi xue za zhi - 11 Apr 2006
Xu Hong, Qian Yuan, Xu Hang, Zhang Jia-huai, Zhu Ru-nan, Wang Fang
Abstract excerpt
OBJECTIVE: To study the resistance to amantadine of epidemic strain of H3 subtype influenza virus. METHODS: Forty-one strains of influenza virus were isolated from pediatric patients with influenza in Beijing 2004-2005 and were identified as H3 subtype. RNA was extracted. Thirty of the 40 strains were resistant to amantadine with a resistance rate of 75%. The M2 gene ion channel fragments were amplified by...
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