Article
Amantadine- and oseltamivir-resistant variants of influenza A viruses in Thailand.
Biochemical and biophysical research communications - 18 Dec 2009
Bai Gui-Rong, Chittaganpitch Malinee, Kanai Yuta, Li Yong-Gang, Auwanit Wattana, Ikuta Kazuyoshi, Sawanpanyalert Pathom
Abstract excerpt
Amantadine and oseltamivir are used to treat influenza A virus infections; however, resistance to these drugs has been widely reported throughout the world. In this study, the frequency and genetic characteristics of the drug-resistant influenza A viruses that circulated in Thailand from 2006 to 2008 were investigated. The nucleotide sequences of the NA and M2 genes were elucidated in order to identify mutations...
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