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Article

Apolipoprotein e genotype, plasma cholesterol, and cancer: a Mendelian randomization study.

American journal of epidemiology - 1 Dec 2009

Trompet Stella, Jukema J Wouter, Katan Martijn B, Blauw Gerard J, Sattar Naveed, Buckley Brendan, Caslake Muriel, Ford Ian, Shepherd Jim, Westendorp Rudi G J, de Craen Anton J M

Abstract excerpt

Observational studies have shown an association between low plasma cholesterol levels and increased risk of cancer, whereas most randomized clinical trials involving cholesterol-lowering medications have not shown this association. Between 1997 and 2002, the authors assessed the association between plasma cholesterol levels and cancer risk, free from confounding and reverse causality, in a Mendelian randomization...

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Identifiers

PMID: 19889709
DOI: 10.1093/aje/kwp294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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