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Article

Association of an apolipoprotein E polymorphism with circulating cholesterols and hypertension: a meta-based Mendelian randomization analysis.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2012

Niu Wenquan, Zhang Xuezhi, Qi Yue

Abstract excerpt

Prospective studies have reported that circulating cholesterol abnormalities are predictive of hypertension. As a test of the causal influence of circulating cholesterols on hypertension, we used a meta-based Mendelian randomization analysis to determine whether the apolipoprotein E (ApoE) gene polymorphism ɛ2/ɛ3/ɛ4 related to cholesterol changes is associated with hypertension. Data were available from 17 study...

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Identifiers

PMID: 22113353
DOI: 10.1038/hr.2011.202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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