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Article

Effects of APOE gene ε4 allele on serum lipid profiles and risk of cardiovascular disease and tumorigenesis in southern Chinese population.

World journal of surgical oncology - 3 Sept 2022

Gan Caiyan, Zhang Yinmei, Liang Fei, Guo Xuemin, Zhong Zhixiong

Abstract excerpt

BACKGROUND: Human apolipoprotein E (APOE) polymorphisms are attributable to the presence of three common alleles, namely, ε2, ε3, and ε4, which generate six genotypes, viz, E2/E2, E2/E3, E3/E3, E3/E4, E4/E4, and E2/E4. APOE polymorphisms are associated with all types of tumors and cardiovascular diseases (CVD). However, the relationship between the type of APOE polymorphisms and tumorigenesis remains debatable....

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Identifiers

PMID: 36057714
DOI: 10.1186/s12957-022-02748-2
PMCID: PMC9440530

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