Article
Morphological and biochemical features of obesity are associated with mineralization genes' polymorphisms.
International journal of obesity (2005) - 1 Aug 2010
Korostishevsky M, Cohen Z, Malkin I, Ermakov S, Yarenchuk O, Livshits G
Abstract excerpt
BACKGROUND: Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) was recently extensively studied as a candidate gene for obesity phenotypes. As the human homologue of the mouse progressive ankylosis (ANKH) and alkaline phosphatase (ALPL) are known functional partners of ENPP1 in bone mineralization, we hypothesized that these genes may also be jointly involved in determining obesity features. AIM: To...
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