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Article

A systematic review and cross-database analysis of single nucleotide polymorphisms underlying hip morphology and osteoarthritis reveals shared mechanisms.

Osteoarthritis and cartilage - 1 Aug 2024

Verleyen Marlies, He Yukun, Burssens Arne, Silva Marta Santana, Callewaert Bert, Audenaert Emmanuel

Abstract excerpt

OBJECTIVE: Understanding the mechanisms of hip disease, such as osteoarthritis (OA), is crucial to advance their treatment. Such hip diseases often involve specific morphological changes. Genetic variations, called single nucleotide polymorphisms (SNPs), influence various hip morphological parameters. This study investigated the biological relevance of SNPs correlated to hip morphology in genome-wide association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 38852879
DOI: 10.1016/j.joca.2024.05.010

Genes

BMP7
GDF5
SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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