Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.

PloS one - 2 Nov 2009

Paun Bogdan C, Cheng Yulan, Leggett Barbara A, Young Joanne, Meltzer Stephen J, Mori Yuriko

Abstract excerpt

BACKGROUND: Coding region microsatellite instability (MSI) results in loss of gene products and promotion of microsatellite-unstable (MSI-H) carcinogenesis. Recent studies have indicated that MSI within 3'-untranslated regions (3'UTRs) may post-transcriptionally dysregulate gene products. Within this context, we conducted a broad mutational survey of 42 short 3'UTR microsatellites (MSs) in 45 MSI-H colorectal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Autophagy-Related Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Intestinal Mucosa

Share to Microsatellite Instability

Share to Microsatellite Repeats

Share to Protein-Tyrosine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 19888451
DOI: 10.1371/journal.pone.0007715
PMCID: PMC2766054

Genes

NUAK1
RTF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.PMID 19888451Read ↗

Candidate driver genes in microsatellite‐unstable colorectal cancerSemantic proximity Read ↗

mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerSemantic proximity Read ↗

Coding microsatellite instability analysis in microsatellite unstable small intestinal adenocarcinomas identifies MARCKS as a common target of inactivation.Semantic proximity Read ↗

Microsatellite instability at U2AF-binding polypyrimidic tract sites perturbs alternative splicing during colorectal cancer initiation.Semantic proximity Read ↗

Correlations between microsatellite instability and the biological behaviour of tumoursSemantic proximity Read ↗

Colorectal Cancers with Microsatellite Instability Display Unique miRNA ProfilesSemantic proximity Read ↗

Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapySemantic proximity Read ↗

Systematic identification of genes with coding microsatellites mutated in DNA mismatch repair-deficient cancer cells.Semantic proximity Read ↗

Classification and characterization of microsatellite instability across 18 cancer types.Semantic proximity Read ↗

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer.Semantic proximity Read ↗

Sporadic colorectal adenocarcinomas with high-frequency microsatellite instabilitySemantic proximity Read ↗

Dissecting microsatellite instability in colorectal cancer: one size does not fit all.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.