Article
Leptin--2548 g/A polymorphism in endometrial cancer.
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti - 1 Jan 2009
Chovanec J, Bienertová-Vasků J A, Dostálová Z
Abstract excerpt
BACKGROUND: Previously, the polymorphism-2548 G/A within the promoter of the leptin (LEP) gene was reported to be associated with overweight and obesity, the factors significantly associated to increased endometrial cancer risk. Leptin has been described to play an important role in signal transduction in endometrial cancer cells indicating that leptin promotes endometrial cancer growth and invasiveness and...
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