Association of Single Nucleotide Polymorphism -2548 G/A (rs12112075) of leptin gene with endometrial cancer and uterine leiomyomas.

doi:10.1016/j.ejogrb.2017.09.022

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Article

Association of Single Nucleotide Polymorphism -2548 G/A (rs12112075) of leptin gene with endometrial cancer and uterine leiomyomas.

European journal of obstetrics, gynecology, and reproductive biology - 1 Nov 2017

Bieńkiewicz Jan, Romanowicz Hanna, Malinowski Andrzej, Smolarz Beata

Abstract excerpt

AIM: The aim of this study was to analyse the frequencies of genotypes and alleles of Single Nucleotide Polymorphism (SNP) -2548 G/A (rs12112075) of leptin gene (LEP) and an attempt to evaluate the effect this DNA marker has on endometrial cancer (EC) and uterine leiomyomas (UL). MATERIAL AND METHODS: The study comprised 120 patients treated for endometrial cancer and 90 patients treated for uterine leiomyomas....

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PMID: 28964972
DOI: 10.1016/j.ejogrb.2017.09.022

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