Article
No association between XRCC1 and XRCC3 gene polymorphisms and breast cancer risk: Iowa Women's Health Study.
Cancer detection and prevention - 1 Jan 2006
Thyagarajan Bharat, Anderson Kristin E, Folsom Aaron R, Jacobs David R, Lynch Charles F, Bargaje Archana, Khaliq Waseem, Gross Myron D
Abstract excerpt
BACKGROUND: Genetic variation in DNA repair may contribute to differences in the susceptibility of several cancers. We evaluated two polymorphisms in the base excision repair pathway (BER) (XRCC1; Arg194Trp and Arg399Gln) and one polymorphism in the double strand DNA repair pathway (XRCC3; Thr241Met) for their association with breast cancer risk. METHODS: The association was analyzed in a nested case control...
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