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Article

Phenotypic re-expression of near quiescent chondrocytes: The effects of type II collagen and growth factors.

Journal of biomaterials applications - 1 Jul 2010

Wong Chin-Chean, Chiu Li-Hsuan, Lai Wen-Fu T, Tsai Tsung-Tan, Fang Chia-Lang, Chen Shih-Ching, Tsai Yu-Hui

Abstract excerpt

After extensively expanding in monolayer culture, the cultured chondrocytes become quiescent. The aim of this study was to establish the hypothesis that the phenotypic function of extensively expanded primary chondrocytes may be restored with extracellular matrix (ECM) compositions with or without growth factors. The restoring effects of these microenvironmental factors on the near quiescent passage 9 (P9)...

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Identifiers

PMID: 19726528
DOI: 10.1177/0885328209343611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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