Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: dose dependence and involvement of myc and ras.

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Article

Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: dose dependence and involvement of myc and ras.

Cancer research - 1 Feb 1991

Breuer M, Wientjens E, Verbeek S, Slebos R, Berns A

Abstract excerpt

Transgenic mice overexpressing the pim-1 oncogene in their lymphoid compartments are predisposed to T-cell lymphomagenesis but only to the extent that approximately 10% of the transgenic mice develop lymphomas within 34 weeks after birth. Recently, we have shown that lymphomagenesis in pim-1 tran...

Topics

Animals
Base Sequence
Codon
DNA Probes
Dose-Response Relationship, Drug
Ethylnitrosourea
Gene Expression Regulation, Neoplastic
Genes, myc
Genes, ras
Lymphoma, T-Cell
Mice
Mice, Transgenic
Molecular Sequence Data
Moloney murine leukemia virus
Mutation

Source

Open in PubMed

Identifiers

PMID: 1988138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1988138-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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