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Article

Conditional Transgenic Expression of PIM1 Kinase in Prostate Induces Inflammation-Dependent Neoplasia

2 Apr 2013

Abstract excerpt

The Pim proteins are a family of highly homologous protein serine/threonine kinases that have been found to be overexpressed in cancer. Elevated levels of Pim1 kinase were first discovered in human leukemia and lymphomas. However, more recently Pim1 was found to be increased in solid tumors, including pancreatic and prostate cancers, and has been proposed as a prognostic marker. Although the Pim kinases have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23565217
DOI: 10.1371/journal.pone.0060277

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