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Article

Tumorigenesis in transgenic mice: identification and characterization of synergizing oncogenes.

Journal of cellular biochemistry - 1 Oct 1991

Berns A

Abstract excerpt

Transgenic mice carrying oncogenes present a useful model with which to assess the tissue-specific action of oncogenes. These mice are usually predisposed to a specific type of neoplastic growth. The tumors that arise are usually monoclonal in origin and become only apparent after a variable latency period, suggesting that additional events are required for tumor formation. Identification of these additional...

Topics

Animals
DNA Transposable Elements
Genes, Viral
Leukemia Virus, Murine
Lymphoma
Mice
Mice, Transgenic
Mutation
Oncogenes
Proto-Oncogenes
Recombination, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1661736
DOI: 10.1002/jcb.240470206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1661736-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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