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Article

Biomedical engineering strategies in system design space.

Annals of biomedical engineering - 1 Apr 2011

Savageau Michael A

Abstract excerpt

Modern systems biology and synthetic bioengineering face two major challenges in relating properties of the genetic components of a natural or engineered system to its integrated behavior. The first is the fundamental unsolved problem of relating the digital representation of the genotype to the analog representation of the parameters for the molecular components. For example, knowing the DNA sequence does not...

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Identifiers

PMID: 21203848
DOI: 10.1007/s10439-010-0220-2
PMCID: PMC3074507

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