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Article

Development and validation of a CpG island methylator phenotype-related prognostic signature for cholangiocarcinoma.

Journal of cellular physiology - 1 Apr 2021

Liang Junnan, Liu Tongtong, Liao Jingyu, Zhang Lu, Zhou Mi, Xu Weiqi, He Yi, Cai Guangzhen, Jin Guannan, Song Jia, Li Ganxun, Liang Huifang, Ding Zeyang, Zhang Bixiang

Abstract excerpt

Cholangiocarcinoma (CCA) still has a very unfavorable prognosis with a very high mortality, which is complicated by a lack of prognostic biomarkers. In this study, CCA patients in the Gene Expression Omnibus (GEO) cohort were categorized into two subtypes. Differentially expressed and methylated genes were identified, and the impact of DNA methylation in the trans-regulation of gene expression was investigated....

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Identifiers

PMID: 32996133
DOI: 10.1002/jcp.30082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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