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Article

Baseline brain perfusion and the serotonin transporter promoter polymorphism.

Biological psychiatry - 15 Feb 2010

Viviani Roberto, Sim Eun-Jin, Lo Hanna, Beschoner Petra, Osterfeld Nadine, Maier Christiane, Seeringer Angela, Godoy Ana Leonor, Rosa Araceli, Comas David, Kirchheiner Julia

Abstract excerpt

BACKGROUND: The serotonin transporter length repeat polymorphism (5-HTTLPR) in the promoter region of the serotonin transporter gene (SLC6A4) has been associated in healthy subjects with changes in basal perfusion levels in the limbic system and ventral prefrontal areas, regions involved in the pathophysiology of depression and anxiety, suggesting the existence of a neurobiological trait predisposing to these...

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Identifiers

PMID: 19878929
DOI: 10.1016/j.biopsych.2009.08.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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