Prion protein gene polymorphism in healthy and BSE-affected Slovak cattle.

doi:10.1007/BF03195695

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Article

Prion protein gene polymorphism in healthy and BSE-affected Slovak cattle.

Journal of applied genetics - 1 Jan 2009

Hresko S, Mojzis M, Tkacikova L

Abstract excerpt

Variation of the PrP gene was examined in healthy and BSE-affected Slovak cattle. According to previous studies, the 23-bp indel polymorphism is supposed to be associated with higher susceptibility to BSE. We investigated 301 samples from healthy cattle of various Slovak breeds and 24 samples obtained from tissues of BSE-affected cattle in Slovakia. We examined the PrP gene for the 23-bp indel polymorphism in the...

Topics

Alleles
Animals
Base Sequence
Cattle
DNA Primers
Encephalopathy, Bovine Spongiform
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Heterozygote
Homozygote
INDEL Mutation
Introns
Male
Polymorphism, Genetic
Prions
Repetitive Sequences, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 19875887
DOI: 10.1007/BF03195695

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