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Article

Characterization of 23-bp and 12-bp insertion/deletion polymorphisms in the prion protein gene (PRNP) of Jeju Black cattle.

Research in veterinary science - 1 Oct 2026

Jeong Min-Ju, Memon Sameeullah, Do Kyoungtag, Kim Nameun, Jeong Byung-Hoon

Abstract excerpt

Host genetic factors are known to influence susceptibility to prion diseases. The prion protein gene (PRNP) contains polymorphisms associated with susceptibility across various host species. In cattle, a 23-bp insertion/deletion polymorphism (indel) in the promoter region and a 12-bp indel in intron 1 have been associated with susceptibility to bovine spongiform encephalopathy (BSE). This study aimed to...

Read the complete abstract on PubMed

Topics

Animals
Cattle
Polymorphism, Genetic
INDEL Mutation
Encephalopathy, Bovine Spongiform
Haplotypes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Prions

Gene Frequency

Republic of Korea

Genotype

Prion Proteins

Source

Identifiers

PMID: 42437559
DOI: 10.1016/j.rvsc.2026.106324

Genes

PRNP

Provenance

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