Article
Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds.
Neurogenetics - 1 Feb 2004
Sander Petra, Hamann Henning, Pfeiffer Ina, Wemheuer Wilhelm, Brenig Bertram, Groschup Martin H, Ziegler Ute, Distl Ottmar, Leeb Tosso
Abstract excerpt
Different alleles of the prion protein gene (PRNP) of human and sheep are known to be associated with varying susceptibilities to transmissible spongiform encephalopathies. However, no polymorphisms in the bovine PRNP gene with an effect on susceptibility to prion diseases have been identified to date. In this study we investigated such polymorphisms in German cattle; 48 healthy animals from six different German...
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