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Article

The exon-3 deleted growth hormone receptor polymorphism predisposes to long-term complications of acromegaly.

The Journal of clinical endocrinology and metabolism - 1 Dec 2009

Wassenaar M J E, Biermasz N R, Pereira A M, van der Klaauw A A, Smit J W A, Roelfsema F, van der Straaten T, Cazemier M, Hommes D W, Kroon H M, Kloppenburg M, Guchelaar H-J, Romijn J A

Abstract excerpt

OBJECTIVE: The aim of the study was to evaluate the impact of the genomic deletion of exon 3 of the GH receptor (d3GHR) on long-term clinical outcome of acromegaly in a well-characterized cohort of patients with long-term remission of acromegaly. DESIGN: We conducted a cross-sectional study. METH...

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Identifiers

PMID: 19864451
DOI: 10.1210/jc.2009-1172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19864451-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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