Article
Investigation of the vitamin D receptor polymorphisms in acromegaly patients.
BioMed research international - 1 Jan 2015
Ilhan Muzaffer, Toptas-Hekimoglu Bahar, Yaylim Ilhan, Turgut Seda, Turan Saime, Karaman Ozcan, Tasan Ertugrul
Abstract excerpt
OBJECTIVE: The genetic structural alterations in the majority of somatotroph adenomas are not clarified and the search for novel candidate genes is still a challenge. We aimed to investigate possible associations between vitamin D receptor (VDR) polymorphisms and acromegaly. DESIGN, PATIENTS, AND METHODS: 52 acromegaly patients (mean age 45.7 ± 1.9 years) and 83 controls (mean age 43.1 ± 2.6 years) were recruited...
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