Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

D3 GH receptor polymorphism is not associated with IGF1 levels in untreated acromegaly.

European journal of endocrinology - 1 Aug 2009

Kamenicky Peter, Dos Santos Christine, Espinosa Consuelo, Salenave Sylvie, Galland Françoise, Le Bouc Yves, Maison Patrick, Bougnères Pierre, Chanson Philippe

Abstract excerpt

CONTEXT: A discrepancy between serum GH and IGF1 concentrations is frequent in patients with acromegaly. Here, we examined whether the exon 3-deleted (d3) GH receptor (GHR) variant, which has been linked to increased responsiveness to GH treatment in short children, influences the GH/IGF1 relationship in patients with acromegaly. OBJECTIVE: To study the possible influence of the GHR genotype on the GH/IGF1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Young Adult
Share to Acromegaly

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carrier Proteins

Share to Human Growth Hormone

Share to Insulin-Like Growth Factor I

Share to Linear Models

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 19439509
DOI: 10.1530/EJE-09-0053

Genes

IGF1
GHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

D3 GH receptor polymorphism is not associated with IGF1 levels in untreated acromegaly.PMID 19439509Read ↗

Growth hormone (GH) receptor isoform in acromegaly: lower concentrations of GH but not insulin-like growth factor-1 in patients with a genomic deletion of exon 3 in the GH receptor gene.Semantic proximity Read ↗

The clinical and cardiometabolic effects of d3-growth hormone receptor polymorphism in acromegaly.Semantic proximity Read ↗

Clinical and biochemical impact of the d3 growth hormone receptor genotype in acromegaly.Semantic proximity Read ↗

d3-Growth hormone receptor polymorphism in acromegaly: effects on metabolic phenotype.Semantic proximity Read ↗

Influence of growth hormone receptor (GHR) exon 3 and -202A/C IGFBP-3 genetic polymorphisms on clinical and biochemical features and therapeutic outcome of patients with acromegaly.Semantic proximity Read ↗

The exon 3-deleted growth hormone receptor is associated with better response to pegvisomant therapy in acromegaly.Semantic proximity Read ↗

The distribution of exon 3-deleted/full-length growth hormone receptor polymorphism in the Turkish population.Semantic proximity Read ↗

The exon-3 deleted growth hormone receptor polymorphism predisposes to long-term complications of acromegaly.Semantic proximity Read ↗

The Exon 3-Deleted Growth Hormone Receptor (d3GHR) Polymorphism - a Favorable Backdoor Mechanism for the GHR FunctionSemantic proximity Read ↗

The Growth Response to Growth Hormone (GH) Treatment in Children with Isolated GH Deficiency Is Independent of the Presence of the Exon 3-Minus Isoform of the GH ReceptorSemantic proximity Read ↗

The growth hormone receptor exon 3-deleted/full-length polymorphism and response to growth hormone therapy in prepubertal idiopathic short children.Semantic proximity Read ↗

Growth hormone receptor variants and response to pegvisomant in monotherapy or in combination with somatostatin analogs in acromegalic patients: a multicenter study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.