Article
The clinical and cardiometabolic effects of d3-growth hormone receptor polymorphism in acromegaly.
Pituitary - 1 Feb 2015
Cinar Nese, Dagdelen Selcuk, Yorgun Hikmet, Canpolat Ugur, Kabakçı Giray, Erbas Tomris
Abstract excerpt
PURPOSE: Exon 3-deleted GH receptor variant (d3-GHR) is associated with increased responsiveness to exogenous GH. The aim of this study was to determine the effect of d3-GHR polymorphism on the GH/IGF-1 relationship, clinical parameters, and comorbidity in acromegalic patients. METHODS: The study included 118 acromegalic patients (61 female and 57 male; mean age: 50.3 ± 12.2 years) and 108 healthy controls (94...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
