Article
Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation.
Journal of virology - 1 Jan 2001
Sheaffer A K, Newcomb W W, Gao M, Yu D, Weller S K, Brown J C, Tenney D J
Abstract excerpt
Packaging of DNA into preformed capsids is a fundamental early event in the assembly of herpes simplex virus type 1 (HSV-1) virions. Replicated viral DNA genomes, in the form of complex branched concatemers, and unstable spherical precursor capsids termed procapsids are thought to be the substrates for the DNA-packaging reaction. In addition, seven viral proteins are required for packaging, although their...
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