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Article

Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology.

The European journal of neuroscience - 1 Nov 2009

Leduc Valérie, Théroux Louise, Dea Doris, Robitaille Yves, Poirier Judes

Abstract excerpt

Evidence suggests that the genes involved in brain lipid homeostasis are of particular relevance for Alzheimer's disease (AD) etiology. Among these genes, that encoding paraoxonase 1 (PON1) has gained newfound interest from a public health perspective, as recent studies have suggested that PON1 L55M and Q192R genetic variants might affect individual susceptibility to environmental events, such as exposure to...

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Identifiers

PMID: 19863653
DOI: 10.1111/j.1460-9568.2009.06983.x

Genes

PON1

Variants

Provenance

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Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology.PMID 19863653Read ↗

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Lack of an association between Paraoxonase 1 gene polymorphisms (Q192R, L55M) and Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Using Alzgene-like approaches to investigate susceptibility genes for vascular cognitive impairment.Semantic proximity Read ↗

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