Article
The influences of CD14 -260C>T polymorphism on survival in ICU critically ill patients.
Immunological investigations - 1 Jan 2009
Fallavena Paulo R V, Borges Thiago J, Paskulin Diego D, Paludo Francis J O, Goetze Thayse B, de Oliveira Jarbas R, Nóbrega Otávio T, Dias Fernando S, Alho Clarice S
Abstract excerpt
In order to analyze the effect of the two different versions of the cluster of differentiation 14 (CD14) receptor recognizing gene on survival, we determined the -260C>T single nucleotide polymorphism (SNP) frequencies in 514 critically ill patients. We compared the -260TT homozygotes with -260C allele carriers (-260CC and -260CT genotypes) and we demonstrated--260TT patients had the highest survival rate (82% vs...
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