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Article

Population-scale variability of the human UDP-glycosyltransferase gene family.

Journal of genetics and genomics = Yi chuan xue bao - 1 Nov 2024

González-Padilla Daianna, Camara Mahamadou D, Lauschke Volker M, Zhou Yitian

Abstract excerpt

Human UDP-glycosyltransferases (UGTs) are responsible for the glycosylation of a wide variety of endogenous substrates and commonly prescribed drugs. Different genetic polymorphisms in UGT genes are implicated in interindividual differences in drug response and cancer risk. However, the genetic complexity beyond these variants has not been comprehensively assessed. We here leveraged whole-exome and whole-genome...

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PMID: 38969258
DOI: 10.1016/j.jgg.2024.06.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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