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Article

Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes.

BMC evolutionary biology - 2 May 2007

Li Can, Wu Qiang

Abstract excerpt

BACKGROUND: The human genome contains a large number of gene clusters with multiple-variable-first exons, including the drug-metabolizing UDP glucuronosyltransferase (UGT1) and I-branching beta-1,6-N-acetylglucosaminyltransferase (GCNT2, also known as IGNT) clusters, organized in a tandem array, similar to that of the protocadherin (PCDH), immunoglobulin (IG), and T-cell receptor (TCR) clusters. To gain insight...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17475008
DOI: 10.1186/1471-2148-7-69
PMCID: PMC1885805

Genes

GCNT2

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