Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cep55 stabilization is required for normal execution of cytokinesis.

Cell cycle (Georgetown, Tex.) - 15 Nov 2009

van der Horst Armando, Simmons Jacinta, Khanna Kum Kum

Abstract excerpt

Cep55 is a mitotic phosphoprotein that plays an important role in cytokinesis, the final stage of cell division during which physical separation of the two daughter cells is accomplished. We recently demonstrated that the peptidyl-prolyl isomerase Pin1 regulates this cell cycle event by enhancing the Plk1-dependent phosphorylation of Cep55. We show here that Cep55 is stabilized post-translationally during mitosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Cytokinesis
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HeLa Cells

Share to NIMA-Interacting Peptidylprolyl Isomerase

Share to Peptidylprolyl Isomerase

Share to Polo-Like Kinase 1

Share to RNA, Small Interfering

Source

Identifiers

PMID: 19855176
DOI: 10.4161/cc.8.22.10047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cep55 stabilization is required for normal execution of cytokinesis.PMID 19855176Read ↗

The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55Semantic proximity Read ↗

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancerSemantic proximity Read ↗

The Loss of PIN1 Deregulates Cyclin E and Sensitizes Mouse Embryo Fibroblasts to Genomic InstabilitySemantic proximity Read ↗

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins.Semantic proximity Read ↗

Plk1 overexpression induces chromosomal instability and suppresses tumor developmentSemantic proximity Read ↗

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.Semantic proximity Read ↗

The protein kinase kin1 is required for cellular symmetry in fission yeast.Semantic proximity Read ↗

Pin1 acts catalytically to promote a conformational change in Cdc25.Semantic proximity Read ↗

Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis.Semantic proximity Read ↗

The role of the master cancer regulator Pin1 in the development and treatment of cancerSemantic proximity Read ↗

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.Semantic proximity Read ↗

Role of the protein kinase Kin1 and nuclear centering in actomyosin ring formation in fission yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.