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Article

Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis.

The Journal of biological chemistry - 18 Oct 2013

Estey Mathew P, Di Ciano-Oliveira Caterina, Froese Carol D, Fung Karen Y Y, Steels Jonathan D, Litchfield David W, Trimble William S

Abstract excerpt

Precise cell division is essential for multicellular development, and defects in this process have been linked to cancer. Septins are a family of proteins that are required for mammalian cell division, but their function and mode of regulation during this process are poorly understood. Here, we demonstrate that cyclin-dependent kinase 1 (Cdk1) phosphorylates septin 9 (SEPT9) upon mitotic entry, and this...

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Identifiers

PMID: 23990466
DOI: 10.1074/jbc.M113.474932
PMCID: PMC3798476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis.PMID 23990466Read ↗

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