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Article

A conserved sequence in caveolin-1 is both necessary and sufficient for caveolin polarity and cell directional migration.

FEBS letters - 19 Nov 2009

Sun Xing-Hui, Liu Zi-Yang, Chen Hong, Beardsley Andrew R, Qi Qi, Liu Jun

Abstract excerpt

Caveolin-1 (Cav-1) plays an important role in the organization of signaling molecules involved in a variety of signaling pathways, including those mediating cell motility. Here we show that amino acids K47-K57 of Cav-1 are a highly conserved sequence in Cav-1 and Cav-3 proteins, and that expression of either K47-K57 deletion Cav-1 mutant or wild-type Cav-2 that lacks this sequence exhibits a non-polarized...

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PMID: 19854179
DOI: 10.1016/j.febslet.2009.10.055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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