Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.

doi:10.1038/oby.2009.359

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Article

Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.

Obesity (Silver Spring, Md.) - 1 Apr 2010

Johansson Asa, Marroni Fabio, Hayward Caroline, Franklin Christopher S, Kirichenko Anatoly V, Jonasson Inger, Hicks Andrew A, Vitart Veronique, Isaacs Aaron, Axenovich Tatiana, Campbell Susan, Floyd Jamie, Hastie Nick, Knott Sara, Lauc Gordan, Pichler Irene, Rotim Kresimir, Wild Sarah H, Zorkoltseva Irina V, Wilson James F, Rudan Igor, Campbell Harry, Pattaro Cristian, Pramstaller Peter, Oostra Ben A, Wright Alan F, van Duijn Cornelia M, Aulchenko Yurii S, Gyllensten Ulf

Abstract excerpt

As major risk-factors for diabetes and cardiovascular diseases, the genetic contribution to obesity-related traits has been of interest for decades. Recently, a limited number of common genetic variants, which have replicated in different populations, have been identified. One approach to increase the statistical power in genetic mapping studies is to focus on populations with increased levels of linkage...

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PMID: 19851299
DOI: 10.1038/oby.2009.359

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MGAT1

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