Article
Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci.
International journal of obesity (2005) - 1 Nov 2009
Kettunen J, Perola M, Martin N G, Cornes B K, Wilson S G, Montgomery G W, Benyamin B, Harris J R, Boomsma D, Willemsen G, Hottenga J-J, Slagboom P E, Christensen K, Kyvik K O, Sørensen T I A, Pedersen N L, Magnusson P K E, Andrew T, Spector T D, Widen E, Silventoinen K, Kaprio J, Palotie A, Peltonen L
Abstract excerpt
OBJECTIVE: To identify common loci and potential genetic variants affecting body mass index (BMI, kg m(-2)) in study populations originating from Europe. DESIGN: We combined genome-wide linkage scans of six cohorts from Australia, Denmark, Finland, the Netherlands, Sweden and the United Kingdom with an approximately 10-cM microsatellite marker map. Variance components linkage analysis was carried out with age,...
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