Article
The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes.
Molecular medicine (Cambridge, Mass.) - 20 Jan 2021
Ludwig-Słomczyńska Agnieszka H, Seweryn Michał T, Kapusta Przemysław, Pitera Ewelina, Mantaj Urszula, Cyganek Katarzyna, Gutaj Paweł, Dobrucka Łucja, Wender-Ożegowska Ewa, Małecki Maciej T, Wołkow Paweł P
Abstract excerpt
BACKGROUND: Clinical data suggest that BMI and gestational weight gain (GWG) are strongly interconnected phenotypes; however, the genetic basis of the latter is rather unclear. Here we aim to find genes and genetic variants which influence BMI and/or GWG. METHODS: We have genotyped 316 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays. The GIANT, ARIC and T2D-GENES summary statistics were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.