Synergistic interaction between aflatoxin B<sub>1</sub> and hepatitis B virus in hepatocarcinogenesis

doi:10.1111/j.1478-3231.2003.00869.x

Article

Synergistic interaction between aflatoxin B<sub>1</sub> and hepatitis B virus in hepatocarcinogenesis

27 Nov 2003

Abstract excerpt

Chronic hepatitis B virus (HBV) infection and dietary exposure to aflatoxin B1 (AFB1), two of the major risk factors in the multifactorial aetiology of hepatocellular carcinoma (HCC), co-exist in those countries with the highest incidences of and the youngest patients with this tumour, raising the possibility of a synergistic carcinogenic interaction between the two agents. Experimental studies in HBV-transgenic...

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