Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant BRAF(T1799A) can be detected in the blood of papillary thyroid carcinoma patients and correlates with disease status.

The Journal of clinical endocrinology and metabolism - 1 Dec 2009

Cradic Kendall W, Milosevic Dragana, Rosenberg Anne M, Erickson Lori A, McIver Bryan, Grebe Stefan K G

Abstract excerpt

CONTEXT: The BRAF(T1799A) transversion is the most frequent morphotype-specific somatic mutation in papillary thyroid carcinoma (PTC). The ability to detect this mutation in the circulation could aid in diagnosis and follow-up of PTC patients. OBJECTIVE: Our objective was to develop and clinically validate a sensitive and specific assay for the detection of BRAF(T1799A) in blood samples from PTC patients. DESIGN:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Thyroglobulin

Share to Thyroid Function Tests

Share to Thyroid Hormones

Share to Thyroid Neoplasms

Share to Thyrotropin

Source

Identifiers

PMID: 19850689
DOI: 10.1210/jc.2009-1349

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant BRAF(T1799A) can be detected in the blood of papillary thyroid carcinoma patients and correlates with disease status.PMID 19850689Read ↗

Detection of Circulating BRAF(V600E) in Patients with Papillary Thyroid Carcinoma.Semantic proximity Read ↗

Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF(V599lns)).Semantic proximity Read ↗

Detection of plasma BRAF(V600E) mutation is associated with lung metastasis in papillary thyroid carcinomas.Semantic proximity Read ↗

Prevalence, tumorigenic role, and biochemical implications of rare BRAF alterations.Semantic proximity Read ↗

Analysis of circulating tumor DNA does not improve the clinical management of patients with locally advanced and metastatic papillary thyroid carcinoma.Semantic proximity Read ↗

Circulating BRAFV600E in the diagnosis and follow-up of differentiated papillary thyroid carcinoma.Semantic proximity Read ↗

BRAF (V600E) mutation analysis in papillary thyroid carcinomas by peptide nucleic acid clamp real-time PCR.Semantic proximity Read ↗

Significance of allelic percentage of BRAF c.1799T > A (V600E) mutation in papillary thyroid carcinoma.Semantic proximity Read ↗

BRAF mutation testing of thyroid fine-needle aspiration biopsy specimens for preoperative risk stratification in papillary thyroid cancer.Semantic proximity Read ↗

The Frequency and Clinical Implications of the BRAFV600EMutation in Papillary Thyroid Cancer Patients in Korea Over the Past Two DecadesSemantic proximity Read ↗

Detection of BRAF V600E activating mutation in papillary thyroid carcinoma using PCR with allele-specific fluorescent probe melting curve analysis.Semantic proximity Read ↗

Evaluation of molecular diagnostic approaches for the detection of BRAF p.V600E mutations in papillary thyroid cancer: Clinical implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.