Article
BRAF (V600E) mutation analysis in papillary thyroid carcinomas by peptide nucleic acid clamp real-time PCR.
Annals of surgical oncology - 1 Mar 2013
Jeong Dongjun, Jeong Yujun, Park Ji Hye, Han Sun Wook, Kim Sung Yong, Kim Yeo Joo, Kim Sang Jin, Hwangbo Young, Park Soyoung, Cho Hyun Deuk, Oh Mee Hye, Yang Seung Ha, Kim Chang Jin
Abstract excerpt
BACKGROUND: Activating somatic mutation of the BRAF (V600E) has been identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a variable frequency (32-87%) in different series by different methods. The BRAF (V600E) mutation is associated with various clinicopathological parameters. The mutation is an important factor for the management of the PTC patients. The objective of this study...
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