Article
Analysis of circulating tumor DNA does not improve the clinical management of patients with locally advanced and metastatic papillary thyroid carcinoma.
Head & neck - 1 Aug 2018
Condello Vincenzo, Macerola Elisabetta, Ugolini Clara, De Napoli Luigi, Romei Cristina, Materazzi Gabriele, Elisei Rossella, Basolo Fulvio
Abstract excerpt
BACKGROUND: Circulating cell-free tumor DNA (ctDNA) in plasma is a promising noninvasive instrument for cancer monitoring. Detection of BRAFV600E on ctDNA of patients with papillary thyroid carcinoma (PTC) may represent an indicator of tumor aggressiveness and progression. METHODS: Eighty-three plasma samples were collected from 70 patients with thyroid nodules undergoing surgery and from 13 patients with PTC...
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