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Article

Detection of plasma BRAF(V600E) mutation is associated with lung metastasis in papillary thyroid carcinomas.

Yonsei medical journal - 1 May 2015

Kim Bo Hyun, Kim In Joo, Lee Byung Joo, Lee Jin Choon, Kim In Suk, Kim Seong-Jang, Kim Won Jin, Jeon Yun Kyung, Kim Sang Soo, Kim Yong Ki

Abstract excerpt

PURPOSE: The BRAF(V600E) mutation represents a novel indicator of the progression and aggressiveness of papillary thyroid carcinoma (PTC). The purpose of this study was to determine the clinical significance of free circulating mutant BRAF(V600E) in predicting the advanced disease of PTC. MATERIALS AND METHODS: Seventy seven matched tumor and plasma samples obtained from patients with both benign and PTC were...

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Identifiers

PMID: 25837167
DOI: 10.3349/ymj.2015.56.3.634
PMCID: PMC4397431

Genes

BRAF

Variants

Provenance

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