Article
Twinstar, the Drosophila homolog of cofilin/ADF, is required for planar cell polarity patterning.
Development (Cambridge, England) - 1 May 2006
Blair Adrienne, Tomlinson Andrew, Pham Hung, Gunsalus Kristin C, Goldberg Michael L, Laski Frank A
Abstract excerpt
Planar cell polarity (PCP) is a level of tissue organization in which cells adopt a uniform orientation within the plane of an epithelium. The process of tissue polarization is likely to be initiated by an extracellular gradient. Thus, determining how cells decode and convert this graded information into subcellular asymmetries is key to determining how cells direct the reorganization of the cytoskeleton to...
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