Article
CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids.
The American journal of clinical nutrition - 1 Dec 2009
Garaulet Marta, Lee Yu-Chi, Shen Jian, Parnell Laurence D, Arnett Donna K, Tsai Michael Y, Lai Chao-Qiang, Ordovas Jose M
Abstract excerpt
BACKGROUND: Disruption of the circadian system may be causal for manifestations of the metabolic syndrome (MetS). OBJECTIVE: The objective was to study the associations of 5 CLOCK polymorphisms with MetS features by analyzing fatty acid (FA) composition from dietary and red blood cell (RBC) membrane sources. DESIGN: Participants (n = 1100) in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) study...
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