Article
Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome.
Chronobiology international - 1 Apr 2014
Garcia-Rios Antonio, Gomez-Delgado Francisco Jesus, Garaulet Marta, Alcala-Diaz Juan Francisco, Delgado-Lista Francisco Javier, Marin Carmen, Rangel-Zuñiga Oriol Alberto, Rodriguez-Cantalejo Fernando, Gomez-Luna Purificacion, Ordovas Jose Maria, Perez-Jimenez Francisco, Lopez-Miranda Jose, Perez-Martinez Pablo
Abstract excerpt
Genetic variation at the Circadian Locomotor Output Cycles Kaput (CLOCK) locus has been associated with lifestyle-related conditions such as obesity, metabolic syndrome (MetS) and cardiovascular diseases. In fact, it has been suggested that the disruption of the circadian system may play a causal role in manifestations of MetS. The aim of this research was to find out whether habitual consumption of a low-fat...
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