Article
Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
The American journal of clinical nutrition - 1 Feb 2015
Mozaffarian Dariush, Kabagambe Edmond K, Johnson Catherine O, Lemaitre Rozenn N, Manichaikul Ani, Sun Qi, Foy Millennia, Wang Lu, Wiener Howard, Irvin Marguerite R, Rich Stephen S, Wu Hongyu, Jensen Majken K, Chasman Daniel I, Chu Audrey Y, Fornage Myriam, Steffen Lyn, King Irena B, McKnight Barbara, Psaty Bruce M, Djoussé Luc, Chen Ida Y-D, Wu Jason H Y, Siscovick David S, Ridker Paul M, Tsai Michael Y, Rimm Eric B, Hu Frank B, Arnett Donna K
Abstract excerpt
BACKGROUND: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent influences (e.g., relating to incorporation, metabolism, or intercompetition with other fatty acids) that could alter circulating concentrations and possibly modulate or mediate impacts on health. OBJECTIVE: The...
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