Article
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population.
Diabetes research and clinical practice - 1 Sept 2012
Ho Janice S K, Germer Soren, Tam Claudia H T, So Wing-Yee, Martin Mitchell, Ma Ronald C W, Chan Juliana C N, Ng Maggie C Y
Abstract excerpt
AIMS: We examined the risk association between single nucleotide polymorphisms (SNPs) in eleven candidate genes with type 2 diabetes (T2D). T2D-associated polymorphisms were also examined for prediction of incident CHD. METHODS: 113 tagging SNPs were genotyped in stage 1 (467 T2D cases, 290 controls), and 15 SNPs were analyzed in the final cohort (1462 T2D cases, 600 controls). Three T2D-associated SNPs were...
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