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Article

Autoimmune-mediated intestinal inflammation-impact and regulation of antigen-specific CD8+ T cells.

Gastroenterology - 1 Aug 2006

Westendorf Astrid Maria, Fleissner Diana, Deppenmeier Stefanie, Gruber Achim Dieter, Bruder Dunja, Hansen Wiebke, Liblau Roland, Buer Jan

Abstract excerpt

BACKGROUND & AIMS: Few data exist regarding mechanisms of mucosal CD8+ T-cell reactivity to epithelial-specific antigen. To dissect the immunologic mechanisms underlying CD8+ T-cell dysregulation, reactivity to a self-antigen expressed in intestinal epithelium of mice bearing a major histocompatibility complex class I-restricted T-cell receptor specific for this antigen was studied. In addition, antigen-specific...

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Identifiers

PMID: 16890605
DOI: 10.1053/j.gastro.2006.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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